24/02/2021

Strategies to escape viral infection in archaea

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  • ORGANISATION NAME
    Hector Fellow Academy
  • ORGANISATION COUNTRY
    Germany
  • FUNDING TYPE
    Funding
  • DEADLINE DATE
    15/04/2021
  • RESEARCH FIELD
    Natural sciences
  • CAREER STAGE
    First Stage Researcher (R1) (Up to the point of PhD)

Description

Strategies to escape viral infection in archaea

Project description:

In this project you will work with archaea and their viruses isolated from hypersaline environments. Archaea are ubiquitous micro-organisms, which are found in moderate environments as well as in extreme habitats. The viruses of archaea are characterized by a high morphological diversity. There is still very little known of the infection mechanisms of archaeal viruses. We study how these viruses infect cells of halophilic archaea, and how they recognize and attach to their host cell. With a combination of molecular biology, microbiology, electron- and light microscopy tools, the selected applicant will study the importance of the cell surface for viral entry. Specifically, the PhD student will focus on the changes at the archaeal cell surface that are required for viral resistance. This will give insight into mechanisms of defense against viruses acting at the cell surface, and will help to understand how viruses can contribute to the evolution of the archaeal cell surface.

Keywords:

Archaea, archaeal virus, virus-host interaction, infection mechanism, biofilm formation

Entry requirements:

MSc degree in Biology, Molecular Biology, Biochemistry or equivalent. Affinity for microbiology, virology and molecular biology are important. Practical experience in these fields is a plus. The applicant should be willing to bring research visits to collaborating laboratories in other countries to perform part of their experiments.

Location:

Faculty of Biology, Albert Ludwig University of Freiburg, Freiburg, Germany

Starting date:

September 1st 2021

Funding:

limited to 3 years

How to apply?

Please apply via the HFA application portal.

The Hector Research Career Development Awardees will arrange interviews (via skype or if feasible in-person) with the most promising applicants. The final candidates will be invited for a personal presentation on July 8, 2021 in Bremen (Germany). The final decisions will be announced by August 2021.

Application Deadline:

April 15th, 2021

Enquiries:

For questions related to making your application, please contact Hector Fellow Academy Office: application@hectorfellow-academy.de or www.hector-fellow-academy.de

Disclaimer:

The responsibility for the funding offers published on this website, including the funding description, lies entirely with the publishing institutions. The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.