• Being able to understand and predict ligand-protein interactions and translate the molecular understanding into structure-activity relationships and structure-kinetics relationships.
• Experience in fragment-based drug design and structure-based drug design and developing detailed structure-activity relationships.
• Experience in applying a wide variety of CADD techniques, including protein-structure predictions, molecular dynamics, free-energy perturbations, structural chemogenomics, machine learning, AI, etc.
• Data management expertise, cheminformatics and bioinformatics.
• Able and eager to discuss results with colleagues who perform synthesis and screening.
• Good communicative skills in writing and speaking and the ability to motivate and teach colleagues and undergraduate students

As a university, we strive for equal opportunities for all, recognizing that diversity takes many forms. We believe that diversity in all its complexity is invaluable for the quality of our teaching, research and service. We are always looking for talent with diverse backgrounds and experiences. This also means that we are committed to creating an inclusive community so that we can use diversity as an asset.

We realize that each individual brings a unique set of skills, expertise and mindset. Therefore we are happy to invite anyone who recognizes themselves in the profile to apply, even if you do not meet all the requirements.

A challenging position in a socially engaged organisation. At VU Amsterdam, you contribute to education, research and service for a better world. And that is valuable. So in return for your efforts, we offer you:

• a salary of minimum € 3.546,00 (Scale 10) and maximum € 5.538,00 (Scale 10) gross per month, on a full-time basis. This is based on UFO profile Researcher 4. The exact salary depends on your education and experience.
• a position for at least 0.8 FTE. Your employment contract will initially last 1 year.

We also offer you attractive fringe benefits and regulations. Some examples:

• A full-time 38-hour working week comes with a holiday leave entitlement of 232 hours per year. If you choose to work 40 hours, you have 96 extra holiday leave hours on an annual basis. For part-timers, this is calculated pro rata.
• 8% holiday allowance and 8.3% end-of-year bonus
• space for personal development
• a wide range of sports facilities which staff may use at a modest charge
• discount on (and occasionally exclusive access to) theater performances and courses at the Griffioen Cultural Center

We would like to receive a CV, a motivation letter, and the contact information for two or three referees.

The start of the position is no later than September 2026.

Acquisition in response to this advertisement is not appreciated.